Evidence for small RNAs homologous to effector-encoding genes and transposable elements in the oomycete Phytophthora infestans.
Identifieur interne : 001541 ( Main/Exploration ); précédent : 001540; suivant : 001542Evidence for small RNAs homologous to effector-encoding genes and transposable elements in the oomycete Phytophthora infestans.
Auteurs : Ramesh R. Vetukuri [Suède] ; Anna K M. Sman ; Christian Tellgren-Roth ; Sultana N. Jahan ; Johan Reimeg Rd ; Johan Fogelqvist ; Eugene Savenkov ; Fredrik Söderbom ; Anna O. Avrova ; Stephen C. Whisson ; Christina DixeliusSource :
- PloS one [ 1932-6203 ] ; 2012.
Descripteurs français
- KwdFr :
- ARN (génétique), Cartographie chromosomique (méthodes), Génome bactérien (MeSH), Interférence par ARN (MeSH), Lycopersicon esculentum (MeSH), Maladies des plantes (microbiologie), Modèles biologiques (MeSH), Modèles génétiques (MeSH), Oomycetes (métabolisme), Petit ARN non traduit (génétique), Phytophthora infestans (métabolisme), Solanum tuberosum (MeSH), Séquences répétées terminales (MeSH), Séquençage nucléotidique à haut débit (méthodes), Technique de Northern (MeSH), microARN (métabolisme), Éléments transposables d'ADN (MeSH).
- MESH :
- génétique : ARN, Petit ARN non traduit.
- microbiologie : Maladies des plantes.
- métabolisme : Oomycetes, Phytophthora infestans, microARN.
- méthodes : Cartographie chromosomique, Séquençage nucléotidique à haut débit.
- Génome bactérien, Interférence par ARN, Lycopersicon esculentum, Modèles biologiques, Modèles génétiques, Solanum tuberosum, Séquences répétées terminales, Technique de Northern, Éléments transposables d'ADN.
English descriptors
- KwdEn :
- Blotting, Northern (MeSH), Chromosome Mapping (methods), DNA Transposable Elements (MeSH), Genome, Bacterial (MeSH), High-Throughput Nucleotide Sequencing (methods), Lycopersicon esculentum (MeSH), MicroRNAs (metabolism), Models, Biological (MeSH), Models, Genetic (MeSH), Oomycetes (metabolism), Phytophthora infestans (metabolism), Plant Diseases (microbiology), RNA (genetics), RNA Interference (MeSH), RNA, Small Untranslated (genetics), Solanum tuberosum (MeSH), Terminal Repeat Sequences (MeSH).
- MESH :
- chemical , genetics : RNA, RNA, Small Untranslated.
- chemical , metabolism : MicroRNAs.
- chemical : DNA Transposable Elements.
- metabolism : Oomycetes, Phytophthora infestans.
- methods : Chromosome Mapping, High-Throughput Nucleotide Sequencing.
- microbiology : Plant Diseases.
- Blotting, Northern, Genome, Bacterial, Lycopersicon esculentum, Models, Biological, Models, Genetic, RNA Interference, Solanum tuberosum, Terminal Repeat Sequences.
Abstract
Phytophthora infestans is the oomycete pathogen responsible for the devastating late blight disease on potato and tomato. There is presently an intense research focus on the role(s) of effectors in promoting late blight disease development. However, little is known about how they are regulated, or how diversity in their expression may be generated among different isolates. Here we present data from investigation of RNA silencing processes, characterized by non-coding small RNA molecules (sRNA) of 19-40 nt. From deep sequencing of sRNAs we have identified sRNAs matching numerous RxLR and Crinkler (CRN) effector protein genes in two isolates differing in pathogenicity. Effector gene-derived sRNAs were present in both isolates, but exhibited marked differences in abundance, especially for CRN effectors. Small RNAs in P. infestans grouped into three clear size classes of 21, 25/26 and 32 nt. Small RNAs from all size classes mapped to RxLR effector genes, but notably 21 nt sRNAs were the predominant size class mapping to CRN effector genes. Some effector genes, such as PiAvr3a, to which sRNAs were found, also exhibited differences in transcript accumulation between the two isolates. The P. infestans genome is rich in transposable elements, and the majority of sRNAs of all size classes mapped to these sequences, predominantly to long terminal repeat (LTR) retrotransposons. RNA silencing of Dicer and Argonaute genes provided evidence that generation of 21 nt sRNAs is Dicer-dependent, while accumulation of longer sRNAs was impacted by silencing of Argonaute genes. Additionally, we identified six microRNA (miRNA) candidates from our sequencing data, their precursor sequences from the genome sequence, and target mRNAs. These miRNA candidates have features characteristic of both plant and metazoan miRNAs.
DOI: 10.1371/journal.pone.0051399
PubMed: 23272103
PubMed Central: PMC3522703
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Evidence for small RNAs homologous to effector-encoding genes and transposable elements in the oomycete Phytophthora infestans.</title><author><name sortKey="Vetukuri, Ramesh R" sort="Vetukuri, Ramesh R" uniqKey="Vetukuri R" first="Ramesh R" last="Vetukuri">Ramesh R. Vetukuri</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plant Biology and Forest Genetics, Uppsala BioCenter, Swedish University of Agricultural Sciences and Linnean Center for Plant Biology, Uppsala, Sweden. Ramesh.Vetukuri@slu.se</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Plant Biology and Forest Genetics, Uppsala BioCenter, Swedish University of Agricultural Sciences and Linnean Center for Plant Biology, Uppsala</wicri:regionArea><wicri:noRegion>Uppsala</wicri:noRegion></affiliation></author><author><name sortKey=" Sman, Anna K M" sort=" Sman, Anna K M" uniqKey=" Sman A" first="Anna K M" last=" Sman">Anna K M. Sman</name></author><author><name sortKey="Tellgren Roth, Christian" sort="Tellgren Roth, Christian" uniqKey="Tellgren Roth C" first="Christian" last="Tellgren-Roth">Christian Tellgren-Roth</name></author><author><name sortKey="Jahan, Sultana N" sort="Jahan, Sultana N" uniqKey="Jahan S" first="Sultana N" last="Jahan">Sultana N. Jahan</name></author><author><name sortKey="Reimeg Rd, Johan" sort="Reimeg Rd, Johan" uniqKey="Reimeg Rd J" first="Johan" last="Reimeg Rd">Johan Reimeg Rd</name></author><author><name sortKey="Fogelqvist, Johan" sort="Fogelqvist, Johan" uniqKey="Fogelqvist J" first="Johan" last="Fogelqvist">Johan Fogelqvist</name></author><author><name sortKey="Savenkov, Eugene" sort="Savenkov, Eugene" uniqKey="Savenkov E" first="Eugene" last="Savenkov">Eugene Savenkov</name></author><author><name sortKey="Soderbom, Fredrik" sort="Soderbom, Fredrik" uniqKey="Soderbom F" first="Fredrik" last="Söderbom">Fredrik Söderbom</name></author><author><name sortKey="Avrova, Anna O" sort="Avrova, Anna O" uniqKey="Avrova A" first="Anna O" last="Avrova">Anna O. Avrova</name></author><author><name sortKey="Whisson, Stephen C" sort="Whisson, Stephen C" uniqKey="Whisson S" first="Stephen C" last="Whisson">Stephen C. Whisson</name></author><author><name sortKey="Dixelius, Christina" sort="Dixelius, Christina" uniqKey="Dixelius C" first="Christina" last="Dixelius">Christina Dixelius</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2012">2012</date><idno type="RBID">pubmed:23272103</idno><idno type="pmid">23272103</idno><idno type="doi">10.1371/journal.pone.0051399</idno><idno type="pmc">PMC3522703</idno><idno type="wicri:Area/Main/Corpus">001374</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">001374</idno><idno type="wicri:Area/Main/Curation">001374</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">001374</idno><idno type="wicri:Area/Main/Exploration">001374</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Evidence for small RNAs homologous to effector-encoding genes and transposable elements in the oomycete Phytophthora infestans.</title><author><name sortKey="Vetukuri, Ramesh R" sort="Vetukuri, Ramesh R" uniqKey="Vetukuri R" first="Ramesh R" last="Vetukuri">Ramesh R. Vetukuri</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plant Biology and Forest Genetics, Uppsala BioCenter, Swedish University of Agricultural Sciences and Linnean Center for Plant Biology, Uppsala, Sweden. Ramesh.Vetukuri@slu.se</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Plant Biology and Forest Genetics, Uppsala BioCenter, Swedish University of Agricultural Sciences and Linnean Center for Plant Biology, Uppsala</wicri:regionArea><wicri:noRegion>Uppsala</wicri:noRegion></affiliation></author><author><name sortKey=" Sman, Anna K M" sort=" Sman, Anna K M" uniqKey=" Sman A" first="Anna K M" last=" Sman">Anna K M. Sman</name></author><author><name sortKey="Tellgren Roth, Christian" sort="Tellgren Roth, Christian" uniqKey="Tellgren Roth C" first="Christian" last="Tellgren-Roth">Christian Tellgren-Roth</name></author><author><name sortKey="Jahan, Sultana N" sort="Jahan, Sultana N" uniqKey="Jahan S" first="Sultana N" last="Jahan">Sultana N. Jahan</name></author><author><name sortKey="Reimeg Rd, Johan" sort="Reimeg Rd, Johan" uniqKey="Reimeg Rd J" first="Johan" last="Reimeg Rd">Johan Reimeg Rd</name></author><author><name sortKey="Fogelqvist, Johan" sort="Fogelqvist, Johan" uniqKey="Fogelqvist J" first="Johan" last="Fogelqvist">Johan Fogelqvist</name></author><author><name sortKey="Savenkov, Eugene" sort="Savenkov, Eugene" uniqKey="Savenkov E" first="Eugene" last="Savenkov">Eugene Savenkov</name></author><author><name sortKey="Soderbom, Fredrik" sort="Soderbom, Fredrik" uniqKey="Soderbom F" first="Fredrik" last="Söderbom">Fredrik Söderbom</name></author><author><name sortKey="Avrova, Anna O" sort="Avrova, Anna O" uniqKey="Avrova A" first="Anna O" last="Avrova">Anna O. Avrova</name></author><author><name sortKey="Whisson, Stephen C" sort="Whisson, Stephen C" uniqKey="Whisson S" first="Stephen C" last="Whisson">Stephen C. Whisson</name></author><author><name sortKey="Dixelius, Christina" sort="Dixelius, Christina" uniqKey="Dixelius C" first="Christina" last="Dixelius">Christina Dixelius</name></author></analytic><series><title level="j">PloS one</title><idno type="eISSN">1932-6203</idno><imprint><date when="2012" type="published">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Blotting, Northern (MeSH)</term><term>Chromosome Mapping (methods)</term><term>DNA Transposable Elements (MeSH)</term><term>Genome, Bacterial (MeSH)</term><term>High-Throughput Nucleotide Sequencing (methods)</term><term>Lycopersicon esculentum (MeSH)</term><term>MicroRNAs (metabolism)</term><term>Models, Biological (MeSH)</term><term>Models, Genetic (MeSH)</term><term>Oomycetes (metabolism)</term><term>Phytophthora infestans (metabolism)</term><term>Plant Diseases (microbiology)</term><term>RNA (genetics)</term><term>RNA Interference (MeSH)</term><term>RNA, Small Untranslated (genetics)</term><term>Solanum tuberosum (MeSH)</term><term>Terminal Repeat Sequences (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>ARN (génétique)</term><term>Cartographie chromosomique (méthodes)</term><term>Génome bactérien (MeSH)</term><term>Interférence par ARN (MeSH)</term><term>Lycopersicon esculentum (MeSH)</term><term>Maladies des plantes (microbiologie)</term><term>Modèles biologiques (MeSH)</term><term>Modèles génétiques (MeSH)</term><term>Oomycetes (métabolisme)</term><term>Petit ARN non traduit (génétique)</term><term>Phytophthora infestans (métabolisme)</term><term>Solanum tuberosum (MeSH)</term><term>Séquences répétées terminales (MeSH)</term><term>Séquençage nucléotidique à haut débit (méthodes)</term><term>Technique de Northern (MeSH)</term><term>microARN (métabolisme)</term><term>Éléments transposables d'ADN (MeSH)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>RNA</term><term>RNA, Small Untranslated</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>MicroRNAs</term></keywords><keywords scheme="MESH" type="chemical" xml:lang="en"><term>DNA Transposable Elements</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>ARN</term><term>Petit ARN non traduit</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Oomycetes</term><term>Phytophthora infestans</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Chromosome Mapping</term><term>High-Throughput Nucleotide Sequencing</term></keywords><keywords scheme="MESH" qualifier="microbiologie" xml:lang="fr"><term>Maladies des plantes</term></keywords><keywords scheme="MESH" qualifier="microbiology" xml:lang="en"><term>Plant Diseases</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Oomycetes</term><term>Phytophthora infestans</term><term>microARN</term></keywords><keywords scheme="MESH" qualifier="méthodes" xml:lang="fr"><term>Cartographie chromosomique</term><term>Séquençage nucléotidique à haut débit</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Blotting, Northern</term><term>Genome, Bacterial</term><term>Lycopersicon esculentum</term><term>Models, Biological</term><term>Models, Genetic</term><term>RNA Interference</term><term>Solanum tuberosum</term><term>Terminal Repeat Sequences</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Génome bactérien</term><term>Interférence par ARN</term><term>Lycopersicon esculentum</term><term>Modèles biologiques</term><term>Modèles génétiques</term><term>Solanum tuberosum</term><term>Séquences répétées terminales</term><term>Technique de Northern</term><term>Éléments transposables d'ADN</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Phytophthora infestans is the oomycete pathogen responsible for the devastating late blight disease on potato and tomato. There is presently an intense research focus on the role(s) of effectors in promoting late blight disease development. However, little is known about how they are regulated, or how diversity in their expression may be generated among different isolates. Here we present data from investigation of RNA silencing processes, characterized by non-coding small RNA molecules (sRNA) of 19-40 nt. From deep sequencing of sRNAs we have identified sRNAs matching numerous RxLR and Crinkler (CRN) effector protein genes in two isolates differing in pathogenicity. Effector gene-derived sRNAs were present in both isolates, but exhibited marked differences in abundance, especially for CRN effectors. Small RNAs in P. infestans grouped into three clear size classes of 21, 25/26 and 32 nt. Small RNAs from all size classes mapped to RxLR effector genes, but notably 21 nt sRNAs were the predominant size class mapping to CRN effector genes. Some effector genes, such as PiAvr3a, to which sRNAs were found, also exhibited differences in transcript accumulation between the two isolates. The P. infestans genome is rich in transposable elements, and the majority of sRNAs of all size classes mapped to these sequences, predominantly to long terminal repeat (LTR) retrotransposons. RNA silencing of Dicer and Argonaute genes provided evidence that generation of 21 nt sRNAs is Dicer-dependent, while accumulation of longer sRNAs was impacted by silencing of Argonaute genes. Additionally, we identified six microRNA (miRNA) candidates from our sequencing data, their precursor sequences from the genome sequence, and target mRNAs. These miRNA candidates have features characteristic of both plant and metazoan miRNAs.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">23272103</PMID><DateCompleted><Year>2013</Year><Month>06</Month><Day>26</Day></DateCompleted><DateRevised><Year>2018</Year><Month>11</Month><Day>13</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1932-6203</ISSN><JournalIssue CitedMedium="Internet"><Volume>7</Volume><Issue>12</Issue><PubDate><Year>2012</Year></PubDate></JournalIssue><Title>PloS one</Title><ISOAbbreviation>PLoS One</ISOAbbreviation></Journal><ArticleTitle>Evidence for small RNAs homologous to effector-encoding genes and transposable elements in the oomycete Phytophthora infestans.</ArticleTitle><Pagination><MedlinePgn>e51399</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1371/journal.pone.0051399</ELocationID><Abstract><AbstractText>Phytophthora infestans is the oomycete pathogen responsible for the devastating late blight disease on potato and tomato. There is presently an intense research focus on the role(s) of effectors in promoting late blight disease development. However, little is known about how they are regulated, or how diversity in their expression may be generated among different isolates. Here we present data from investigation of RNA silencing processes, characterized by non-coding small RNA molecules (sRNA) of 19-40 nt. From deep sequencing of sRNAs we have identified sRNAs matching numerous RxLR and Crinkler (CRN) effector protein genes in two isolates differing in pathogenicity. Effector gene-derived sRNAs were present in both isolates, but exhibited marked differences in abundance, especially for CRN effectors. Small RNAs in P. infestans grouped into three clear size classes of 21, 25/26 and 32 nt. Small RNAs from all size classes mapped to RxLR effector genes, but notably 21 nt sRNAs were the predominant size class mapping to CRN effector genes. Some effector genes, such as PiAvr3a, to which sRNAs were found, also exhibited differences in transcript accumulation between the two isolates. The P. infestans genome is rich in transposable elements, and the majority of sRNAs of all size classes mapped to these sequences, predominantly to long terminal repeat (LTR) retrotransposons. RNA silencing of Dicer and Argonaute genes provided evidence that generation of 21 nt sRNAs is Dicer-dependent, while accumulation of longer sRNAs was impacted by silencing of Argonaute genes. Additionally, we identified six microRNA (miRNA) candidates from our sequencing data, their precursor sequences from the genome sequence, and target mRNAs. These miRNA candidates have features characteristic of both plant and metazoan miRNAs.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Vetukuri</LastName><ForeName>Ramesh R</ForeName><Initials>RR</Initials><AffiliationInfo><Affiliation>Department of Plant Biology and Forest Genetics, Uppsala BioCenter, Swedish University of Agricultural Sciences and Linnean Center for Plant Biology, Uppsala, Sweden. Ramesh.Vetukuri@slu.se</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Åsman</LastName><ForeName>Anna K M</ForeName><Initials>AK</Initials></Author><Author ValidYN="Y"><LastName>Tellgren-Roth</LastName><ForeName>Christian</ForeName><Initials>C</Initials></Author><Author ValidYN="Y"><LastName>Jahan</LastName><ForeName>Sultana N</ForeName><Initials>SN</Initials></Author><Author ValidYN="Y"><LastName>Reimegård</LastName><ForeName>Johan</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Fogelqvist</LastName><ForeName>Johan</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Savenkov</LastName><ForeName>Eugene</ForeName><Initials>E</Initials></Author><Author ValidYN="Y"><LastName>Söderbom</LastName><ForeName>Fredrik</ForeName><Initials>F</Initials></Author><Author ValidYN="Y"><LastName>Avrova</LastName><ForeName>Anna O</ForeName><Initials>AO</Initials></Author><Author ValidYN="Y"><LastName>Whisson</LastName><ForeName>Stephen C</ForeName><Initials>SC</Initials></Author><Author ValidYN="Y"><LastName>Dixelius</LastName><ForeName>Christina</ForeName><Initials>C</Initials></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><Agency>Biotechnology and Biological Sciences Research Council</Agency><Country>United Kingdom</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2012</Year><Month>12</Month><Day>14</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>PLoS One</MedlineTA><NlmUniqueID>101285081</NlmUniqueID><ISSNLinking>1932-6203</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D004251">DNA Transposable Elements</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D035683">MicroRNAs</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D058727">RNA, Small Untranslated</NameOfSubstance></Chemical><Chemical><RegistryNumber>63231-63-0</RegistryNumber><NameOfSubstance UI="D012313">RNA</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D015152" MajorTopicYN="N">Blotting, Northern</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002874" MajorTopicYN="N">Chromosome Mapping</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="N">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004251" MajorTopicYN="Y">DNA Transposable Elements</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016680" MajorTopicYN="N">Genome, Bacterial</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D059014" MajorTopicYN="N">High-Throughput Nucleotide Sequencing</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="N">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D018551" MajorTopicYN="N">Lycopersicon esculentum</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D035683" MajorTopicYN="N">MicroRNAs</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008954" MajorTopicYN="N">Models, Biological</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008957" MajorTopicYN="N">Models, Genetic</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009868" MajorTopicYN="N">Oomycetes</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D055750" MajorTopicYN="N">Phytophthora infestans</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010935" MajorTopicYN="N">Plant Diseases</DescriptorName><QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012313" MajorTopicYN="N">RNA</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D034622" MajorTopicYN="N">RNA Interference</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D058727" MajorTopicYN="N">RNA, Small Untranslated</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011198" MajorTopicYN="N">Solanum tuberosum</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D020079" MajorTopicYN="N">Terminal Repeat Sequences</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2012</Year><Month>07</Month><Day>12</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2012</Year><Month>10</Month><Day>31</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2012</Year><Month>12</Month><Day>29</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2012</Year><Month>12</Month><Day>29</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2013</Year><Month>6</Month><Day>28</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">23272103</ArticleId><ArticleId IdType="doi">10.1371/journal.pone.0051399</ArticleId><ArticleId IdType="pii">PONE-D-12-20506</ArticleId><ArticleId IdType="pmc">PMC3522703</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>BMC Biotechnol. 2010;10:64</Citation><ArticleIdList><ArticleId IdType="pubmed">20815927</ArticleId></ArticleIdList></Reference><Reference><Citation>Plant Cell. 2009 Sep;21(9):2928-47</Citation><ArticleIdList><ArticleId IdType="pubmed">19794118</ArticleId></ArticleIdList></Reference><Reference><Citation>Science. 2006 Jan 13;311(5758):195-8</Citation><ArticleIdList><ArticleId IdType="pubmed">16410517</ArticleId></ArticleIdList></Reference><Reference><Citation>RNA. 2010 May;16(5):893-903</Citation><ArticleIdList><ArticleId IdType="pubmed">20354150</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Plant Microbe Interact. 2008 Nov;21(11):1460-70</Citation><ArticleIdList><ArticleId IdType="pubmed">18842095</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Plant Microbe Interact. 2011 Oct;24(10):1132-42</Citation><ArticleIdList><ArticleId IdType="pubmed">21649512</ArticleId></ArticleIdList></Reference><Reference><Citation>Nucleic Acids Res. 2007;35(20):6714-26</Citation><ArticleIdList><ArticleId IdType="pubmed">17916577</ArticleId></ArticleIdList></Reference><Reference><Citation>Nature. 2009 Jan 22;457(7228):413-20</Citation><ArticleIdList><ArticleId IdType="pubmed">19158787</ArticleId></ArticleIdList></Reference><Reference><Citation>Nature. 2009 Sep 17;461(7262):393-8</Citation><ArticleIdList><ArticleId IdType="pubmed">19741609</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2005 Jun;79(11):7227-38</Citation><ArticleIdList><ArticleId IdType="pubmed">15890961</ArticleId></ArticleIdList></Reference><Reference><Citation>EMBO J. 2003 Aug 1;22(15):3983-91</Citation><ArticleIdList><ArticleId IdType="pubmed">12881432</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Rev Genet. 2009 Feb;10(2):94-108</Citation><ArticleIdList><ArticleId IdType="pubmed">19148191</ArticleId></ArticleIdList></Reference><Reference><Citation>BMC Genomics. 2009;10:620</Citation><ArticleIdList><ArticleId IdType="pubmed">20021695</ArticleId></ArticleIdList></Reference><Reference><Citation>Science. 2002 Sep 20;297(5589):2053-6</Citation><ArticleIdList><ArticleId IdType="pubmed">12242443</ArticleId></ArticleIdList></Reference><Reference><Citation>BMC Genomics. 2011;12:288</Citation><ArticleIdList><ArticleId IdType="pubmed">21635781</ArticleId></ArticleIdList></Reference><Reference><Citation>Science. 2007 Jan 12;315(5809):199-200</Citation><ArticleIdList><ArticleId IdType="pubmed">17218517</ArticleId></ArticleIdList></Reference><Reference><Citation>RNA. 2008 Aug;14(8):1508-15</Citation><ArticleIdList><ArticleId IdType="pubmed">18566193</ArticleId></ArticleIdList></Reference><Reference><Citation>Genes Dev. 2010 Nov 15;24(22):2566-82</Citation><ArticleIdList><ArticleId IdType="pubmed">21078820</ArticleId></ArticleIdList></Reference><Reference><Citation>BMC Genomics. 2010;11:637</Citation><ArticleIdList><ArticleId IdType="pubmed">21080964</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2011;6(8):e22870</Citation><ArticleIdList><ArticleId IdType="pubmed">21857960</ArticleId></ArticleIdList></Reference><Reference><Citation>Bioinformatics. 2010 Dec 1;26(23):3002-3</Citation><ArticleIdList><ArticleId IdType="pubmed">20934992</ArticleId></ArticleIdList></Reference><Reference><Citation>Science. 2008 May 23;320(5879):1077-81</Citation><ArticleIdList><ArticleId IdType="pubmed">18403677</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Plant Microbe Interact. 2012 Oct;25(10):1350-60</Citation><ArticleIdList><ArticleId IdType="pubmed">22712506</ArticleId></ArticleIdList></Reference><Reference><Citation>Fungal Genet Biol. 1999 Nov;28(2):94-106</Citation><ArticleIdList><ArticleId IdType="pubmed">10587472</ArticleId></ArticleIdList></Reference><Reference><Citation>Nucleic Acids Res. 2004 Jan 1;32(Database issue):D109-11</Citation><ArticleIdList><ArticleId IdType="pubmed">14681370</ArticleId></ArticleIdList></Reference><Reference><Citation>Science. 2007 Jan 12;315(5809):244-7</Citation><ArticleIdList><ArticleId IdType="pubmed">17158288</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Plant Pathol. 2011 Oct;12(8):772-85</Citation><ArticleIdList><ArticleId IdType="pubmed">21726377</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cell. 1999 Mar;3(3):339-48</Citation><ArticleIdList><ArticleId IdType="pubmed">10198636</ArticleId></ArticleIdList></Reference><Reference><Citation>Microbiology. 2008 Dec;154(Pt 12):3743-51</Citation><ArticleIdList><ArticleId IdType="pubmed">19047742</ArticleId></ArticleIdList></Reference><Reference><Citation>Nature. 2007 Nov 1;450(7166):115-8</Citation><ArticleIdList><ArticleId IdType="pubmed">17914356</ArticleId></ArticleIdList></Reference><Reference><Citation>Plant Cell. 2007 Jun;19(6):1750-69</Citation><ArticleIdList><ArticleId IdType="pubmed">17601824</ArticleId></ArticleIdList></Reference><Reference><Citation>Plant Cell. 2005 May;17(5):1397-411</Citation><ArticleIdList><ArticleId IdType="pubmed">15805478</ArticleId></ArticleIdList></Reference><Reference><Citation>Nature. 2008 May 22;453(7194):539-43</Citation><ArticleIdList><ArticleId IdType="pubmed">18404146</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Rev Genet. 2011 Sep;12(9):615-27</Citation><ArticleIdList><ArticleId IdType="pubmed">21850042</ArticleId></ArticleIdList></Reference><Reference><Citation>Science. 2004 Oct 1;306(5693):79-86</Citation><ArticleIdList><ArticleId IdType="pubmed">15459382</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Genet. 2012 Feb;44(2):157-64</Citation><ArticleIdList><ArticleId IdType="pubmed">22231482</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell. 2002 Aug 23;110(4):513-20</Citation><ArticleIdList><ArticleId IdType="pubmed">12202040</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS Pathog. 2011 Nov;7(11):e1002353</Citation><ArticleIdList><ArticleId IdType="pubmed">22102810</ArticleId></ArticleIdList></Reference><Reference><Citation>Genome Biol. 2011;12(4):221</Citation><ArticleIdList><ArticleId IdType="pubmed">21554756</ArticleId></ArticleIdList></Reference><Reference><Citation>Annu Rev Phytopathol. 2011;49:507-31</Citation><ArticleIdList><ArticleId IdType="pubmed">21663437</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Rev Genet. 2011 Jan;12(1):19-31</Citation><ArticleIdList><ArticleId IdType="pubmed">21116305</ArticleId></ArticleIdList></Reference><Reference><Citation>Annu Rev Plant Biol. 2006;57:19-53</Citation><ArticleIdList><ArticleId IdType="pubmed">16669754</ArticleId></ArticleIdList></Reference><Reference><Citation>Eukaryot Cell. 2009 Oct;8(10):1486-97</Citation><ArticleIdList><ArticleId IdType="pubmed">19666782</ArticleId></ArticleIdList></Reference><Reference><Citation>Science. 2007 Jan 12;315(5809):241-4</Citation><ArticleIdList><ArticleId IdType="pubmed">17124291</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell. 2009 Feb 20;136(4):656-68</Citation><ArticleIdList><ArticleId IdType="pubmed">19239887</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS Pathog. 2012;8(10):e1002940</Citation><ArticleIdList><ArticleId IdType="pubmed">23055926</ArticleId></ArticleIdList></Reference><Reference><Citation>J Mol Evol. 2006 Apr;62(4):388-420</Citation><ArticleIdList><ArticleId IdType="pubmed">16557340</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2012;7(2):e32724</Citation><ArticleIdList><ArticleId IdType="pubmed">22384282</ArticleId></ArticleIdList></Reference><Reference><Citation>Mob Genet Elements. 2012 Mar 1;2(2):110-114</Citation><ArticleIdList><ArticleId IdType="pubmed">22934246</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Rev Microbiol. 2012 Jun;10(6):417-30</Citation><ArticleIdList><ArticleId IdType="pubmed">22565130</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2010 May 25;107(21):9909-14</Citation><ArticleIdList><ArticleId IdType="pubmed">20457921</ArticleId></ArticleIdList></Reference><Reference><Citation>Curr Genet. 2006 Aug;50(2):81-99</Citation><ArticleIdList><ArticleId IdType="pubmed">16691418</ArticleId></ArticleIdList></Reference><Reference><Citation>Plant J. 2011 Jul;67(2):292-304</Citation><ArticleIdList><ArticleId IdType="pubmed">21457371</ArticleId></ArticleIdList></Reference><Reference><Citation>Fungal Genet Biol. 2005 Mar;42(3):244-56</Citation><ArticleIdList><ArticleId IdType="pubmed">15707845</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell. 2004 Jan 23;116(2):281-97</Citation><ArticleIdList><ArticleId IdType="pubmed">14744438</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell. 2010 Feb 19;140(4):504-16</Citation><ArticleIdList><ArticleId IdType="pubmed">20178743</ArticleId></ArticleIdList></Reference><Reference><Citation>Nucleic Acids Res. 2012 Jan;40(1):37-52</Citation><ArticleIdList><ArticleId IdType="pubmed">21911355</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell Res. 2012 Apr;22(4):624-36</Citation><ArticleIdList><ArticleId IdType="pubmed">22410795</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2010 Oct 5;107(40):17421-6</Citation><ArticleIdList><ArticleId IdType="pubmed">20847293</ArticleId></ArticleIdList></Reference><Reference><Citation>Fungal Genet Biol. 2005 Apr;42(4):351-65</Citation><ArticleIdList><ArticleId IdType="pubmed">15749054</ArticleId></ArticleIdList></Reference><Reference><Citation>Int J Syst Evol Microbiol. 2005 Jan;55(Pt 1):487-96</Citation><ArticleIdList><ArticleId IdType="pubmed">15653923</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS Comput Biol. 2009 May;5(5):e1000386</Citation><ArticleIdList><ArticleId IdType="pubmed">19461883</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS Biol. 2007 Mar;5(3):e57</Citation><ArticleIdList><ArticleId IdType="pubmed">17298187</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Biotechnol. 2008 Apr;26(4):407-15</Citation><ArticleIdList><ArticleId IdType="pubmed">18392026</ArticleId></ArticleIdList></Reference><Reference><Citation>EMBO J. 2002 Sep 2;21(17):4671-9</Citation><ArticleIdList><ArticleId IdType="pubmed">12198169</ArticleId></ArticleIdList></Reference><Reference><Citation>Nature. 2004 May 20;429(6989):318-22</Citation><ArticleIdList><ArticleId IdType="pubmed">15152257</ArticleId></ArticleIdList></Reference><Reference><Citation>Nature. 2006 Jul 13;442(7099):203-7</Citation><ArticleIdList><ArticleId IdType="pubmed">16751777</ArticleId></ArticleIdList></Reference><Reference><Citation>J Eukaryot Microbiol. 2005 Sep-Oct;52(5):399-451</Citation><ArticleIdList><ArticleId IdType="pubmed">16248873</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cell. 2004 Oct 8;16(1):69-79</Citation><ArticleIdList><ArticleId IdType="pubmed">15469823</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell Microbiol. 2008 Nov;10(11):2271-84</Citation><ArticleIdList><ArticleId IdType="pubmed">18637942</ArticleId></ArticleIdList></Reference><Reference><Citation>Nucleic Acids Res. 2008 Jan;36(Database issue):D154-8</Citation><ArticleIdList><ArticleId IdType="pubmed">17991681</ArticleId></ArticleIdList></Reference><Reference><Citation>Genome Res. 2011 Sep;21(9):1462-77</Citation><ArticleIdList><ArticleId IdType="pubmed">21685128</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Plant Pathol. 2008 May;9(3):385-402</Citation><ArticleIdList><ArticleId IdType="pubmed">18705878</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Plant Microbe Interact. 1991 Nov-Dec;4(6):602-7</Citation><ArticleIdList><ArticleId IdType="pubmed">1804404</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Plant Pathol. 2005 Mar 1;6(2):153-63</Citation><ArticleIdList><ArticleId IdType="pubmed">20565646</ArticleId></ArticleIdList></Reference><Reference><Citation>Mob DNA. 2011 Oct 19;2(1):12</Citation><ArticleIdList><ArticleId IdType="pubmed">22011512</ArticleId></ArticleIdList></Reference><Reference><Citation>Fungal Genet Biol. 2003 Oct;40(1):4-14</Citation><ArticleIdList><ArticleId IdType="pubmed">12948509</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS Pathog. 2010 May;6(5):e1000920</Citation><ArticleIdList><ArticleId IdType="pubmed">20523899</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell. 2008 Apr 4;133(1):116-27</Citation><ArticleIdList><ArticleId IdType="pubmed">18342361</ArticleId></ArticleIdList></Reference><Reference><Citation>Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4</Citation><ArticleIdList><ArticleId IdType="pubmed">16381832</ArticleId></ArticleIdList></Reference><Reference><Citation>Eukaryot Cell. 2007 Jul;6(7):1200-9</Citation><ArticleIdList><ArticleId IdType="pubmed">17483289</ArticleId></ArticleIdList></Reference><Reference><Citation>Curr Opin Plant Biol. 2011 Aug;14(4):407-14</Citation><ArticleIdList><ArticleId IdType="pubmed">21641854</ArticleId></ArticleIdList></Reference><Reference><Citation>Fungal Biol. 2011 Dec;115(12):1225-33</Citation><ArticleIdList><ArticleId IdType="pubmed">22115441</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Microbiol. 2003 Oct;50(2):487-94</Citation><ArticleIdList><ArticleId IdType="pubmed">14617173</ArticleId></ArticleIdList></Reference><Reference><Citation>Nucleic Acids Res. 2003 Jul 1;31(13):3406-15</Citation><ArticleIdList><ArticleId IdType="pubmed">12824337</ArticleId></ArticleIdList></Reference><Reference><Citation>Nucleic Acids Res. 2011 Jan;39(Database issue):D152-7</Citation><ArticleIdList><ArticleId IdType="pubmed">21037258</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Phylogenet Evol. 2009 Jan;50(1):129-40</Citation><ArticleIdList><ArticleId IdType="pubmed">18977305</ArticleId></ArticleIdList></Reference><Reference><Citation>Microbiology. 2008 May;154(Pt 5):1482-90</Citation><ArticleIdList><ArticleId IdType="pubmed">18451057</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Plant Microbe Interact. 2008 Apr;21(4):433-47</Citation><ArticleIdList><ArticleId IdType="pubmed">18321189</ArticleId></ArticleIdList></Reference><Reference><Citation>Nature. 2006 Jul 13;442(7099):199-202</Citation><ArticleIdList><ArticleId IdType="pubmed">16751776</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20832-7</Citation><ArticleIdList><ArticleId IdType="pubmed">22143776</ArticleId></ArticleIdList></Reference><Reference><Citation>Fungal Genet Biol. 2008 Aug;45(8):1197-205</Citation><ArticleIdList><ArticleId IdType="pubmed">18599326</ArticleId></ArticleIdList></Reference><Reference><Citation>Nature. 2003 Nov 20;426(6964):310-4</Citation><ArticleIdList><ArticleId IdType="pubmed">14628056</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed><affiliations><list><country><li>Suède</li></country></list><tree><noCountry><name sortKey=" Sman, Anna K M" sort=" Sman, Anna K M" uniqKey=" Sman A" first="Anna K M" last=" Sman">Anna K M. Sman</name><name sortKey="Avrova, Anna O" sort="Avrova, Anna O" uniqKey="Avrova A" first="Anna O" last="Avrova">Anna O. Avrova</name><name sortKey="Dixelius, Christina" sort="Dixelius, Christina" uniqKey="Dixelius C" first="Christina" last="Dixelius">Christina Dixelius</name><name sortKey="Fogelqvist, Johan" sort="Fogelqvist, Johan" uniqKey="Fogelqvist J" first="Johan" last="Fogelqvist">Johan Fogelqvist</name><name sortKey="Jahan, Sultana N" sort="Jahan, Sultana N" uniqKey="Jahan S" first="Sultana N" last="Jahan">Sultana N. Jahan</name><name sortKey="Reimeg Rd, Johan" sort="Reimeg Rd, Johan" uniqKey="Reimeg Rd J" first="Johan" last="Reimeg Rd">Johan Reimeg Rd</name><name sortKey="Savenkov, Eugene" sort="Savenkov, Eugene" uniqKey="Savenkov E" first="Eugene" last="Savenkov">Eugene Savenkov</name><name sortKey="Soderbom, Fredrik" sort="Soderbom, Fredrik" uniqKey="Soderbom F" first="Fredrik" last="Söderbom">Fredrik Söderbom</name><name sortKey="Tellgren Roth, Christian" sort="Tellgren Roth, Christian" uniqKey="Tellgren Roth C" first="Christian" last="Tellgren-Roth">Christian Tellgren-Roth</name><name sortKey="Whisson, Stephen C" sort="Whisson, Stephen C" uniqKey="Whisson S" first="Stephen C" last="Whisson">Stephen C. Whisson</name></noCountry><country name="Suède"><noRegion><name sortKey="Vetukuri, Ramesh R" sort="Vetukuri, Ramesh R" uniqKey="Vetukuri R" first="Ramesh R" last="Vetukuri">Ramesh R. Vetukuri</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Bois/explor/PhytophthoraV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001541 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001541 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Bois
|area= PhytophthoraV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:23272103
|texte= Evidence for small RNAs homologous to effector-encoding genes and transposable elements in the oomycete Phytophthora infestans.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:23272103" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a PhytophthoraV1
| This area was generated with Dilib version V0.6.38. |  |